跳转到主要内容
首页

Dedicated to discovery

  • 关于 ELGA
    • 关于 ELGA
    • 招贤纳士
    • 活动
  • 支持
    • 实验室规划
    • 注册产品
    • Register Your Product (USA & Canada Only)
  • 联系信息
  • U.S.A.
  • U.K.
  • Deutschland
  • España
  • France
  • Italia
  • Brasil
  • 日本
首页
  • 产品
    • PURELAB
      • PURELAB® Quest
      • PURELAB® Pharma Compliance
      • PURELAB® Chorus 1 Complete
      • PURELAB® Chorus 1
      • PURELAB® Chorus 2
      • PURELAB® Chorus 2 +
      • PURELAB® Chorus 3
      • PURELAB® flex 1
      • PURELAB® flex 2
      • PURELAB® flex 3
      • PURELAB® flex 4
      • PURELAB® flex 5
    • CENTRA
      • CENTRA® R60/120
      • CENTRA® R200
      • CENTRA® RDS
    • MEDICA
      • MEDICA® 7/15
      • MEDICA® Pro-R & Pro-RE
      • MEDICA® R200
      • MEDICA® EDI 15/30
      • MEDICA® Pro-LPS
      • MEDICA® Pro EDI 60/120
      • MEDICA® BIOX
      • Hubgrade
    • BIOPURE
      • BIOPURE® 300/600
    • ELGA 全产品系列
      • PURELAB® Classic
  • 应用
    • 一般实验室用水要求
    • 临床生物化学
    • 免疫化学
    • 分光光度测定法:
    • 原子光谱分析法
    • 微生物分析
    • 气相色谱分析法
    • 液相色谱
    • 电化学
    • 细胞培养
    • 质谱分析法
    • 遗传学
  • 水纯化技术
    • PureSure
    • 反渗透法
    • 活性碳
    • 电去离子法
    • 离子交换法
    • 紫外线照射法
    • 过滤
  • 水中杂质
    • 微生物和细菌
    • 微粒
    • 无机化合物
    • 有机化合物
    • 溶解气体
  • 知识
    • 博客
    • 案例分析
    • 超纯水
    • 白皮书
  • 认证合作伙伴
  • 联系信息
Home
  • 联系信息
  • 产品
    • PURELAB
      • PURELAB® Quest
      • PURELAB® Pharma Compliance
      • PURELAB® Chorus 1 Complete
      • PURELAB® Chorus 1
      • PURELAB® Chorus 2
      • PURELAB® Chorus 2 +
      • PURELAB® Chorus 3
      • PURELAB® flex 1
      • PURELAB® flex 2
      • PURELAB® flex 3
      • PURELAB® flex 4
      • PURELAB® flex 5
    • CENTRA
      • CENTRA® R60/120
      • CENTRA® R200
      • CENTRA® RDS
    • MEDICA
      • MEDICA® 7/15
      • MEDICA® Pro-R & Pro-RE
      • MEDICA® R200
      • MEDICA® EDI 15/30
      • MEDICA® Pro-LPS
      • MEDICA® Pro EDI 60/120
      • MEDICA® BIOX
      • Hubgrade
    • BIOPURE
      • BIOPURE® 300/600
    • ELGA 全产品系列
      • PURELAB® Classic
  • 应用
    • 一般实验室用水要求
    • 临床生物化学
    • 免疫化学
    • 分光光度测定法:
    • 原子光谱分析法
    • 微生物分析
    • 气相色谱分析法
    • 液相色谱
    • 电化学
    • 细胞培养
    • 质谱分析法
    • 遗传学
  • 水纯化技术
    • PureSure
    • 反渗透法
    • 活性碳
    • 电去离子法
    • 离子交换法
    • 紫外线照射法
    • 过滤
  • 水中杂质
    • 微生物和细菌
    • 微粒
    • 无机化合物
    • 有机化合物
    • 溶解气体
  • 知识
    • 博客
    • 案例分析
    • 超纯水
    • 白皮书
  • 认证合作伙伴
  • 联系信息
  • 关于 ELGA
    • 关于 ELGA
    • 招贤纳士
    • 活动
  • 支持
    • 实验室规划
    • 注册产品
    • Register Your Product (USA & Canada Only)
  • 联系信息
  • U.S.A.
  • U.K.
  • Deutschland
  • España
  • France
  • Italia
  • Brasil
  • 日本
  • 隐私政策
  • 条款和条件
  • 全球法律合规
  • 专利
  • 页面操作员
  • 首页
  • Could Hemp Seeds Provide A Natural Sleep Aid?
Analytical Chemistry
Cool Science

Could Hemp Seeds Provide A Natural Sleep Aid?

25 1月 2021
- by Dr Alison Halliday

Hemp seeds

Researchers validate a simple and reliable new method for extracting and quantifying melatonin in different hemp varieties – finding the highest concentrations in the seeds.

Melatonin or the ‘sleep hormone’ is mainly produced during the night by the pineal gland. As well as helping to regulate our body clocks and sleep patterns, melatonin may also play other important roles in human physiology and health. Some people will be prescribed a synthetic version of melatonin as a treatment for short–term sleep problems – such as insomnia or for the symptoms of jetlag.

Although melatonin has been most extensively studied in animals, it is now known that many plants produce it as well. Since its first detection in 1995, melatonin has been detected in roots, leaves, fruits, flowers, and seeds of a variety of vegetables, cereals, fruits – as well as medicinal herbs. The hormone appears to have many diverse actions in plant physiology, including in growth, rooting, seed germination and photosynthesis.

But while more than 480 constituents have been identified in hemp (Cannabis sativa L.), out of which almost 150 are classified as cannabinoids, there is currently a lack of information about the presence of melatonin in this species.

Examining Melatonin in Hemp

In a new study, published in SN Applied Sciences, researchers set out to develop and validate a simple and reliable method to extract, purify and quantify melatonin in hemp.1 The researchers harvested, dried, and ground the leaves, flower heads and seeds of four different hemp varieties belonging to either legal (fibre type) – or illegal (drug type) chemotypes that contain tetrahydrocannabinol (THC), which is the main psychoactive compound in cannabis.

The team set up a sample preparation procedure which involved methanol extraction and a solid phase clean up protocol to extract the melatonin, followed by quantification using liquid chromatography-electrospray ionization tandem mass spectrometry (LC–ESI/MS/MS). After validating their new protocol in line with international guidelines, they showed that melatonin accumulates highly in hemp seeds, in the range of 13.43 to 30.40 ng/g while the concentration in other samples was much lower. 

As well as solvents and reagents of analytical or the highest grade available, the researchers used ultrapure water generated from an ELGA PURELAB® laboratory water purification system, minimising the risk of adding contaminants that may affect their results.

Potential Sleep Benefits

This study demonstrates the application of a validated new method for quantifying melatonin in hemp varieties belonging to both fibre type and drug type chemotypes. The results demonstrate that hemp seeds contain higher concentrations of melatonin than the aerial parts of the plant, aligning with its essential functions in protecting germ and reproductive tissues.

The highest levels of melatonin were detected in the seeds of a fibre type variety of hemp, suggesting that they have potential as a valuable food source with positive benefits for modulating sleep patterns.

Why Choose ELGA LabWater?

ELGA LabWater has been a trusted name in pure and ultrapure water since 1937. We believe in giving you choice in how you use our water purification solutions, supported by excellent service and support.
 

Reference:

1. Allegrone G, et al. Determination of melatonin content of different varieties of hemp (Cannabis sativa L.) by liquid chromatography tandem mass spectrometry. SN Appl. Sci. (2019):1;720.
 

Dr Alison Halliday

After completing an undergraduate degree in Biochemistry & Genetics at Sheffield University, Alison was awarded a PhD in Human Molecular Genetics at the University of Newcastle. She carried out five years as a Senior Postdoctoral Research Fellow at UCL, investigating the genes involved in childhood obesity syndrome. Moving into science communications, she spent ten years at Cancer Research UK engaging the public about the charity’s work. She now specialises in writing about research across the life sciences, medicine and health.

Quest Download

PURELAB Quest

The only purifier on the market that dispenses all 3 types of science ready water from a compact, economical and easy to use system!

             Click Here To Find Out More

 

  • Enquiry
  • 获取报价
  • 预订演示
  • 联系获认证的合作伙伴

Enquiry

Please check this to confirm that you have read our Terms of Service and Privacy Policy.

获取报价

Please check this to confirm that you have read our Terms of Service and Privacy Policy.

预订演示

Please check this to confirm that you have read our Terms of Service and Privacy Policy.

Call us

Can't find what you are looking for?

Support Number
+44 (0)20 3567 7300
United Kingdom Sales
+44 (0)1628 879 704
United States of America Sales
+1 877-315-3542
France Sales
+33 1 40 83 65 00
China Sales
+86 400-616-8882

 

ELGA LabWater US Headquarters

Lane End Business Park
Lane End, High Wycombe
HP14 3BY
United Kingdom
电话: +44 (0) 203 567 7300
传真:+44 (0) 203 567 7205

Elga LabWater 总部

Lane End Business Park
Lane End, High Wycombe
HP14 3BY
United Kingdom
电话: +44 (0) 203 567 7300
传真:+44 (0) 203 567 7205

案例研究

  • 雅培诊断
  • DASA 医学诊断
  • NeoDIN 医学研究所
  • 北斯塔福德郡 NHS 信托大学医院
  • Olsberg 职业技术学院

资源

  • 了解超纯水
  • 白皮书
  • 水纯化技术
  • 实验室应用
  • 水中杂质

Blogs

  • Latest Blog
  • Water Purity - Different Types of Pure Water
  • What is Clinical Laboratory Reagent Water (CLSI)?
  • What is Total Organic Carbon (TOC)?

© VWS (UK) Ltd. 以 ELGA®LabWater 的名义经营业务。2023- 保留所有权利
ELGA 是 Veolia 旗下全球实验室用水品牌。

  • 隐私政策
  • 条款和条件
  • 全球法律合规
  • 专利
  • 页面操作员
  • 语言
    • Deutsch
    • English
    • Español
    • Français
    • Italiano
    • Português
    • 日本語
    • 中文
  • Veolia 其他站点
    • Veolia
    • Veolia Foundation
    • Veolia Water Technologies
Elga Veolia
TOP

© 2017 ELGA Veolia